Ethylamine → HCID 912857, compound

HRID 1939006Notes

Reaction equation

HRID 1939006 reaction equation
[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=2[C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:16]([NH2:18])[CH3:17]>>[CH2:16]([NH:18][C:9](=[O:11])[C:8]1[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=1[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[CH3:17]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 70357o-Phenylbenzoic acid

Product 1

HCID 912857HCID 912857, compoundYield 94%

Procedure

2-Phenylbenzoic acid was converted to the acid chloride by the procedure of example b. The acid chloride was reacted with 70% aq ethylamine using General Method E1 to afford 10.59 g of N-ethyl-2-phenylbenzamide in 94% yield. m.p. 77°-79° C.

Sources & evidence

ORD record
ord-088fd660651f4001b885fd5861adadc8
Source dataset
uspto-grants-1997_12
Patent number
US05693667

Reaction notes

Loading…