HCID 131719451, compound → HCID 57026151, compound

HRID 1939109Notes

Reaction equation

HRID 1939109 reaction equation
[CH2:1]([CH:3]1[CH:29]=[C:28]([CH3:30])[CH2:27][CH:26]([CH3:31])[CH2:25][CH:24]([O:32][CH3:33])[CH:23]2[O:34][C:19]([OH:38])([CH:20]([CH3:37])[CH2:21][CH:22]2[O:35][CH3:36])[C:18](=[O:39])[C:17](=[O:40])[N:16]2[CH:11]([CH2:12][CH2:13][CH2:14][CH2:15]2)[C:10](=[O:41])[O:9][CH:8]([C:42]([CH3:66])=[CH:43][CH:44]2[CH2:49][CH2:48][CH:47]([O:50][CH2:51][CH:52]([C:54]3[CH:63]=[CH:62][C:61]4[C:56](=[CH:57][CH:58]=[CH:59][CH:60]=4)[CH:55]=3)[OH:53])[CH:46]([O:64][CH3:65])[CH2:45]2)[CH:7]([CH3:67])[CH:6]([O:68][Si](C(C)(C)C)(C)C)[CH2:5][C:4]1=[O:76])[CH3:2]>N1C=CC=CC=1>[CH2:1]([CH:3]1[CH:29]=[C:28]([CH3:30])[CH2:27][CH:26]([CH3:31])[CH2:25][CH:24]([O:32][CH3:33])[CH:23]2[O:34][C:19]([OH:38])([CH:20]([CH3:37])[CH2:21][CH:22]2[O:35][CH3:36])[C:18](=[O:39])[C:17](=[O:40])[N:16]2[CH:11]([CH2:12][CH2:13][CH2:14][CH2:15]2)[C:10](=[O:41])[O:9][CH:8]([C:42]([CH3:66])=[CH:43][CH:44]2[CH2:49][CH2:48][CH:47]([O:50][CH2:51][CH:52]([C:54]3[CH:63]=[CH:62][C:61]4[C:56](=[CH:57][CH:58]=[CH:59][CH:60]=4)[CH:55]=3)[OH:53])[CH:46]([O:64][CH3:65])[CH2:45]2)[CH:7]([CH3:67])[CH:6]([OH:68])[CH2:5][C:4]1=[O:76])[CH3:2]

Participants

3

Reactant 1

HCID 131719451HCID 131719451, compound

Product 1

HCID 57026151HCID 57026151, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The product from Step A was deprotected with HF/pyridine as described in Step B from above to afford 190 mg of the title compound as a colorless solid (1H NMR was consistent with the desired structure).

Sources & evidence

ORD record
ord-0848917080a14569901e33d56b04e12a
Source dataset
uspto-grants-1997_12
Patent number
US05693648

Reaction notes

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