HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-Fluoro-2-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Product | 5-Fluoro-2-methylbenzoyl chloride | HCID 2737383 | — |
Reaction Steps
A mixture of 8.0 g of 5-fluoro-2-methylbenzoic acid and 52 ml of thionyl chloride is heated on a steam bath for 1 hour. The volatiles are removed under vacuum and two times 50 ml of toluene is added and the solvent removed under vacuum to give 8.5 g of product as a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05696112 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-498062d3de134f24a388c84ea92f6b4e |
| Source note | uspto-grants-1997_12 |