HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylhydrazine → 1-Propyl-3-benzyl-8-(1,4benzodioxan-6-yl)xanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylhydrazine | HCID 5976 | — |
| Reactant | 2,3-Dihydro-1,4-benzodioxin-6-carbaldehyde | HCID 248127 | — |
| Reactant | HCID 11254741 | HCID 11254741 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Propyl-3-benzyl-8-(1,4benzodioxan-6-yl)xanthine | HCID 21467223 | 23.9% |
Reaction Steps
2.9 g (0.01 mol) of 1-benzyl-3-propyl-5-nitroso-6-aminouracil are added to 60 ml of dimethylformamide together with 2.3 g (0.014 mol) of 1,4-benzodioxan-6-aldehyde, then 0.5 g (0.014 mol) of 1,1-dimethylhydrazine are added and the mixture is refluxed for 8 hours. After working up in the usual way, the crystalline residue is triturated with ethanol and filtered under suction. 1.0 g of the title compound is obtained in the form of yellow crystals, m.p. 290° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05696124 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-decbfc2b19004f6dadcba42a008db2c8 |
| Source note | uspto-grants-1997_12 |