HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Isothiocyanato-3-(trifluoromethyl)benzene → N-(3-(trifluoromethyl)phenyl)-N'-(2-methoxy-5-(trifluoromethyl)phenyl) thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Isothiocyanato-3-(trifluoromethyl)benzene | HCID 137232 | — |
| Reactant | 2-Methoxy-5-(trifluoromethyl)aniline | HCID 600637 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(3-(trifluoromethyl)phenyl)-N'-(2-methoxy-5-(trifluoromethyl)phenyl) thiourea | HCID 54197929 | 51% |
Reaction Steps
3-(trifluoromethyl)phenyl isothiocyanate in toluene (0.76 ml, 5.0 mmol) was added to a solution of 2-methoxy-5-(trifluoromethyl)aniline in toluene (10 ml). The resulting reaction mixture was stirred at RT overnight and the product was subsequently filtered off. 1.00 g (51%) of the title compound was isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05696138 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-0da55e70336c4445bca4d21c00860d8f |
| Source note | uspto-grants-1997_12 |