HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 53888571, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Chloro-1-benzyl-1H-indole-3-carboxaldehyde | HCID 10563933 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 53888571 | HCID 53888571 | — |
Reaction Steps
To 5.83 g of 1-benzyl-2-chloroindole-3-carbaldehyde, dissolved in 200 ml of abs. EtOH, was added 6.1 g of ethyl 2-cyanoacetate and 6.6 g of triethylamine. After 4 days with stirring, the solution was added to water, and the precipitate collected by filtration and dried to give (1a). Yield 6.72 g of (1a), m.p. 130°-131° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05696148 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-564276ce07ca4794b1f49c067318732d |
| Source note | uspto-grants-1997_12 |