HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 54545595, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 21467584 | HCID 21467584 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54545595 | HCID 54545595 | — |
Reaction Steps
To 500 mg of 1-(3-chlorobenzyl)-2-chloroindole-carbaldehyde, slurried in 10 ml of ethanol, was added 500 mg of potassium carbonate and 0.19 ml of ethyl cyanoacetate. After overnight stirring 10 ml of water was added, and the product collected by filtration, washed with water, and dried to give (10a). Yield 510 mg of (10a). M.p. 130.5°-132° C. (sample recryst. from EtOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05696148 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-0ae9f12da8ea4c9f9350d6814bc2c65f |
| Source note | uspto-grants-1997_12 |