1,4-Dioxane → HCID 67617352, compound

HRID 1939404Notes

Reaction equation

HRID 1939404 reaction equation
C(C(OC1C=C(C)C=CC=1C)C1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1/[C:11](=[CH:16]\[CH3:17])/[C:12]([O:14][CH3:15])=[O:13])(=O)C.O1[CH2:32][CH2:31][O:30][CH2:29][CH2:28]1>>[C:12]([C:11]1[C:16]([CH3:17])=[CH:28][C:29]([O:30][CH2:31][C:32]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2/[C:11](=[CH:16]\[CH3:17])/[C:12]([O:14][CH3:15])=[O:13])=[C:7]([CH3:8])[CH:6]=1)([OH:14])=[O:13]

Participants

3

Reactant 2

HCID 312751,4-DioxaneHCID 67617268HCID 67617268, compound

Product 1

HCID 67617352HCID 67617352, compound

Procedure

In a similar manner to the process for precursor δ), 9.6 g of methyl 2-[2-(acetyl-2,5-dimethylphenoxymethyl)phenyl]-E-but-2-enoate in 60 ml of dioxane were reacted to give the carboxylic acid. After concentrating on a rotary evaporator a yellow oil remained which in addition to 70% of the title compound contained a further 30% of the diacid formed by hydrolysis of the methyl butanoate.

Sources & evidence

ORD record
ord-f7c84784463a4145a8c741477476aa4b
Source dataset
uspto-grants-1997_12
Patent number
US05696161

Reaction notes

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