Cetyl Alcohol → (R)-(-)-2-DECANOL

Participants

Reaction Conditions

Reaction Steps

To the distillation residue, i.e., a mixture of (R)-(-)-2-decanol stearic acid ester and unreacted isopropyl stearate, were added 200 g of palmityl alcohol and 3 g of Lipase PL. After the particle size of the enzyme was regulated by ultrasonication in the same manner as described above, the mixture was stirred at 90° C. and 250 rpm under reduced pressure of 2 mmHg for 24 hours to carry out interesterification while recovering the distillate to obtain free (R)-(-)-2-decanol with high purity (yield: 72%; chemical purity: 99.6%; optical purity: 95% ee).

Provenance & Evidence