HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → alpha-(2-Bromoethyl)-3,4-dichlorophenylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one | HCID 11806496 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | alpha-(2-Bromoethyl)-3,4-dichlorophenylacetic acid | HCID 18936610 | — |
Reaction Steps
Treat the product of Step 1 (21.25 g, 91.96 mmoles) at room temperature with 130 ml. of HOAc saturated with HBr gas. Stir at room temperature for 2 days, then pour into 800 ml. of ice-water with stirring. Store the resultant gum in a freezer for two days, then decant the liquid from the solidified gum. Triturate the solid, filter, wash with water and air dry. Yield: 26.2 g (m.p.=80°-81° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05696267 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-d2e5af3812fb4948ba0da38fe619a48e |
| Source note | uspto-grants-1997_12 |