2-Amino-2-methyl-1,3-propanediol → HCID 131720357, compound

Participants

Reaction Steps

A mixture of 2-amino-2-methyl-1,3-propanediol (5.26 g), oleic acid (33.4 mL) and p-toluenesulfonic acid monohydrate (11.0 g) in toluene (75 mL) was refluxed under nitrogen. Water was separated from the distillate in a Barrett distilling receiver. When the theoretical amount of water (3.3 g) was collected, the heating was stopped and the toluene removed in vacuo on a rotary evaporator. The product was a thick yellow oil.

Provenance & Evidence