HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-4-carboxylic acid → (1,1'-Bi(cyclohexane))-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-4-carboxylic acid | HCID 66724 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (1,1'-Bi(cyclohexane))-4-carboxylic acid | HCID 3062287 | 93.5% |
Reaction Steps
Reduce a solution of 4-biphenylcarboxylic acid (10 g) in ethanol (EtOH) (175 mL) and EtOAc (30 mL) over 5% rhodium/alumina (7 g) under H2 (60 psi) for 8 days. Filter the catalyst and concentrate the solution to obtain the title compound (9.92 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05698548 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-99b5569094014fa7afb6336024ea3b65 |
| Source note | uspto-grants-1997_12 |