Pyridazine-4-carboxylic Acid → HCID 18977191, compound

HRID 1939933Notes

Reaction equation

HRID 1939933 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:13]=[CH:14][C:15](=[O:18])[NH:16][N:17]=2)=[CH:8][CH:7]=1.[N:19]1[CH:24]=[CH:23][C:22]([C:25](O)=[O:26])=[CH:21][N:20]=1>>[N:19]1[CH:24]=[CH:23][C:22]([C:25]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]2[CH:7]=[CH:8][C:9]([C:12]3[CH:13]=[CH:14][C:15](=[O:18])[NH:16][N:17]=3)=[CH:10][CH:11]=2)=[O:26])=[CH:21][N:20]=1

Participants

3

Reactant 2

HCID 2761046Pyridazine-4-carboxylic AcidHCID 18977179HCID 18977179, compound

Product 1

HCID 18977191HCID 18977191, compound

Procedure

By treating 6-[4-(4-aminobutyl)phenyl]pyridazin-3(2H)-one and pyridazin-4-carboxylic acid in the same manner as in Example 87, 6-[4-[4-(pyridazin-4-ylcarbonylamino)butyl]-phenyl]pyridazin-3(2H)-one was obtained.

Sources & evidence

ORD record
ord-a348667628384e6984164576cba122ba
Source dataset
uspto-grants-1997_12
Patent number
US05698554

Reaction notes

Loading…