Aluminium lithium hydride → HCID 21465352, compound

HRID 1939954Notes

Reaction equation

HRID 1939954 reaction equation
[CH2:1]([N:3]([CH2:16][CH3:17])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[C:11]#[N:12])[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:16]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH2:11][NH2:12])[CH3:17]

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 21465378HCID 21465378, compound

Product 1

HCID 21465352HCID 21465352, compoundYield 89%

Procedure

According to a similar manner as that in Reference Example 78, 3-[3-(diethylamino)propoxy]benzonitrile obtained above was reduced by lithium aluminium hydride to give the title compound (89%). This compound was used in the subsequent reaction without further purification.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-e34c2badeadb402a90be5c6c656d0701
Source dataset
uspto-grants-1997_12
Patent number
US05698560

Reaction notes

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