HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethyl-1,4-dioxaspiro[4.5]decan-8-amine → 4-(Dimethylamino)cyclohexan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethyl-1,4-dioxaspiro[4.5]decan-8-amine | HCID 361167 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 4-(Dimethylamino)cyclohexan-1-one | HCID 10374545 | 100% |
Reaction Steps
4.96 gm (26.8 mMol) 4-dimethylamino-1-cyclohexanone ethylene ketal were dissolved in 50 mL formic acid and the solution stirred at reflux for 18 hours. The reaction mixture was then cooled to ambient and the volatiles removed under reduced pressure to give 3.78 gm (100%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05698571 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-4301a70356034a5a90dc9cb2a3ea38ec |
| Source note | uspto-grants-1997_12 |