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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1940041Generated: November 3, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/1940041

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step b, the acid chloride 11 is amidated with morpholine 12 by techniques and procedures well known and appreciated by one of ordinary skill in the art to give the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05698523
Source datasetuspto-grants-1997_12
ORD IDord-a43b9527916b40d5bf108ea96b1aef29
Source noteuspto-grants-1997_12