HCID 21465888, compound → HCID 21465898, compound

Participants

Reaction Steps

To a solution of N-[2-(2-chlorophenyl)-2-(2-nitro-5-chlorophenyl)ethyl]-N-(trifluoroacetyl)glycine methyl ester (1 g) in acetic acid ethyl ester (20 ml) was added 10% Pd/C catalyst (100 mg). The mixture was subjected to catalytic reduction at ambient temperature under atmospheric pressure. After the reaction, the catalyst was removed and the solvent was distilled off. The residue was purified by means of a silica-gel column chromatography (hexane:acetic acid ethyl ester=4:1 v/v as an eluent) to give 0.39 g of an oily compound.

Provenance & Evidence