Potassium Carbonate → HCID 54077540, compound

Participants

Reaction Steps

To dichloromethane (70 ml) were added 3-[N-[2-[1-(2-chlorophenyl)-2-hydroxyethyl]-4-chlorophenyl]-N-neopentylcarbamoyl]acrylic acid ethyl ester (6.8 g), 18-crown-6 (3.78 g) and potassium carbonate. The mixture was stirred for 3 days at room temperature. Insolubles were filtered off, then the solvent was distilled off. The residue was purified by means of a silica-gel column chromatography (hexane:acetic acid ethyl ester=5:1 v/v as an eluent) to give 1.64 g of a non-crystalline solid product.

Provenance & Evidence