HuagongsheHuagongshe Chemistry Print Report · For research reference only
Di-t-butyl[[4-[[N-[3-(1-t-butyloxycarbonylpiperidin-4-yl)propionyl]-N-methylamino]acetyl]-o-phenylene]dioxy]diacetate → {2-Carboxymethoxy-5-[2-(3-piperidin-4-yl-propionylamino)-acetyl]-phenoxy}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Di-t-butyl[[4-[[N-[3-(1-t-butyloxycarbonylpiperidin-4-yl)propionyl]-N-methylamino]acetyl]-o-phenylene]dioxy]diacetate | HCID 21466012 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | {2-Carboxymethoxy-5-[2-(3-piperidin-4-yl-propionylamino)-acetyl]-phenoxy}-acetic acid | HCID 44321683 | 121.2% |
Reaction Steps
The compound prepared in (a) (480 mg) was dissolved in 5 ml of trifluoroacetic acid and treated in the same manner as described in Example 9(b) to give the title compound (380 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05698692 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-53536d0ecfd341b6b4d2cdb0abf7bd46 |
| Source note | uspto-grants-1997_12 |