Sodium Hydroxide → HCID 54409833, compound

HRID 1940378Notes

Reaction equation

C([C:3](CC)([O:7][C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][NH:16][C:17](=[O:33])[CH2:18][CH2:19][CH:20]2[CH2:25][CH2:24][N:23]([C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[CH2:22][CH2:21]2)=[CH:10][C:9]=1[O:34][CH2:35][C:36]([O-:38])=[O:37])[C:4]([O-:6])=[O:5])C.[OH-].[Na+]>>[C:29]([O:28][C:26]([N:23]1[CH2:22][CH2:21][CH:20]([CH2:19][CH2:18][C:17]([NH:16][CH2:15][CH2:14][C:11]2[CH:12]=[CH:13][C:8]([O:7][CH2:3][C:4]([OH:6])=[O:5])=[C:9]([O:34][CH2:35][C:36]([OH:38])=[O:37])[CH:10]=2)=[O:33])[CH2:25][CH2:24]1)=[O:27])([CH3:32])([CH3:30])[CH3:31]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 21466014HCID 21466014, compound

Product 1

HCID 54409833HCID 54409833, compoundYield 89.2%

Procedure

The compound obtained in the above process (a) (150 mg) was hydrolyzed with 1.3 ml of 1N sodium hydroxide to give 121 mg of the title compound.

Sources & evidence

ORD record: ord-316c64b9312a4c7cbb183b2e988d0018
Source dataset: uspto-grants-1997_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05698692

Reaction notes

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