HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methylphenyl)propan-2-amine → N-[1-(4-Methylphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methylphenyl)propan-2-amine | HCID 584050 | — |
| Reactant | S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate | HCID 15380265 | — |
| Product | N-[1-(4-Methylphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide | HCID 67646695 | 88% |
Reaction Steps
Following a procedure similar to that described in Example 3(b), but using S-2pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(4-methylphenyl)-1-methylethylamine (prepared as described in Preparation 10h) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 88%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05698720 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-9d8b01f6d0d24d7eb9914fafbf603805 |
| Source note | uspto-grants-1997_12 |