HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1,2-propanediol → HCID 11428052, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1,2-propanediol | HCID 73561 | — |
| Reactant | 1,3-Benzenedicarboxylic acid, 5-hydroxy-, 1,3-dimethyl ester | HCID 83065 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11428052 | HCID 11428052 | — |
Reaction Steps
Dimethyl 5-hydroxyisophthalate (12.6 g, 60 mmol) was dissolved in methanol (36 mL) containing 3-amino-1,2-dihydroxypropane (16.4 g, 180 mmol). The mixture was heated to reflux temperature for 10 days, and, after cooling to room temperature, was evaporated. Acetone (100 mL) was added to the residue and the crystalline solid was collected by filtration. The product was purified by recrystallization from acetone. Yield 9.0 g (46%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05700448 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-d869b67bc0b54e83b6bde8cf2c027c35 |
| Source note | uspto-grants-1997_12 |