Phenylboronic Acid → HCID 21462922, compound

Participants

Reaction Steps

Ethyl 8-bromo-1-(2,5-dimethoxybenzyl)-4-(4-methoxyphenyl)-1,2-dihydro-2-oxobenzofuro[3,2-b]pyridine-3-carboxylate is reacted analogously to Example 3 with phenylboronic acid to give ethyl 8-phenyl-1-(2,5-dimethoxybenzyl)-4-(4-methoxyphenyl)-1,2-dihydro-2-oxobenzofuro[3,2-b]pyridine-3-carboxylate, m.p. 216°. By ester hydrolysis thereof the 8-phenyl-1-(2,5-dimethoxybenzyl)-4-(4-methoxyphenyl)-1,2-dihydro-2-oxobenzofuro[3,2-b]pyridine-3-carboxylic acid is obtained, m.p. 270°.

Provenance & Evidence