HCID 21463489, compound → HCID 54511624, compound

Participants

Reaction Steps

A solution of 1-(5-amino-2,3-dihydrobenzofuran-7-yl)-3-dimethylaminopropan-1-ol (D 16) (2.12 g) in trifluoroacetic acid (60 ml) was refluxed for 10h, cooled and the solvent evaporated under reduced pressure. The residue was partitioned between 10% Na2CO3 and ethyl acetate, the organic phase was dried (Na2SO4) and the solvent evaporated under reduced pressure, to give the title compound as an orange foam (2.07 g, quantitative).

Provenance & Evidence