HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Amino-2,3-difluorobenzenethiol → Ethyl 3-[(6,7-difluorobenzothiazol-2-yl)methyl]phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Amino-2,3-difluorobenzenethiol | HCID 18435220 | — |
| Reactant | [3-(2-ethoxy-2-oxoethyl)phenyl]acetic Acid | HCID 23086838 | — |
| Product | Ethyl 3-[(6,7-difluorobenzothiazol-2-yl)methyl]phenylacetate | HCID 21463553 | 51.8% |
Reaction Steps
The procedure of Example 16-i) was repeated using 1,3-phenylene diacetic acid monoethyl ester (2.87 g, 10.5 mmol) and 2-amino-5,6-difluorothiophenol (2.0 g, 11.7 mmol) to obtain ethyl 3-[(6,7-difluorobenzothiazol-2-yl)methyl]phenylacetate (1.89 g, 44%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05700819 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-bac7c7a64f744851ab09b14648e14af5 |
| Source note | uspto-grants-1997_12 |