HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenethiol, 2-amino-3,4,6-trifluoro-, hydrochloride → Ethyl 4-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenethiol, 2-amino-3,4,6-trifluoro-, hydrochloride | HCID 11390282 | — |
| Reactant | 2-(4-(2-Ethoxy-2-oxoethyl)phenyl)acetic acid | HCID 59692160 | — |
| Product | Ethyl 4-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]phenylacetate | HCID 21463567 | 35.2% |
Reaction Steps
The procedure of Example 16-i) was repeated using 1,4-phenylene diacetic acid monoethyl ester (510 mg, 2.1 mmol) and 2-amino-3,4,6-trifluorothiophenol hydrochloride (2.0 g, 11.7 mmol) to obtain ethyl 4-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]phenylacetate (270 mg, 35%) as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05700819 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-a44a1a11521a4a2f9dad7b6ba1aee34e |
| Source note | uspto-grants-1997_12 |