HCID 21463762, compound → HCID 21463800, compound

HRID 1940690Notes

Reaction equation

HRID 1940690 reaction equation
[NH2:1][C:2]([NH2:26])=[N:3][C:4](=[O:25])[C:5]1[CH:10]=[C:9]([S:11]([CH3:14])(=[O:13])=[O:12])[C:8]([O:15]CC2C=CC=CC=2)=[CH:7][C:6]=1[CH2:23][CH3:24].[H][H]>C1(C)C=CC=CC=1.[Pd].[C]>[NH2:26][C:2]([NH2:1])=[N:3][C:4](=[O:25])[C:5]1[CH:10]=[C:9]([S:11]([CH3:14])(=[O:13])=[O:12])[C:8]([OH:15])=[CH:7][C:6]=1[CH2:23][CH3:24]

Participants

5

Reactant 2

HCID 21463762HCID 21463762, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21463800HCID 21463800, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 1140TolueneSolvent

Procedure

1.1 g of N-diaminomethylene-2-ethyl-4-benzyloxy-5-methylsulfonylbenzamide (obtainable according to Ex. 6) are dissolved in 30 ml of toluene and treated at room temperature for one hour with hydrogen gas (p=1 atm) under the catalytic action of 150 mg of Pd-carbon (Pd content 1%). The reaction mixture is then filtered, and customary working up gives N-diaminomethylene-2-ethyl-4-hyrdoxy-5-methylsulfonylbenzamide.

Workup

  1. filtrationThe reaction mixture is then filtered

Sources & evidence

ORD record
ord-c4ed568863c240c8974c52794b28d630
Source dataset
uspto-grants-1997_12
Patent number
US05700839

Reaction notes

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