HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethyl)benzoic acid → 2-(Trifluoromethyl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethyl)benzoic acid | HCID 9899 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 2-(Trifluoromethyl)benzoyl chloride | HCID 67561 | — |
Reaction Steps
A solution of 2.0 g of o-trifluoromethylbenzoic acid in 21 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.1 g of the desired product as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05700796 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-006cd1c9b2f0483ea2881bba2e5bf1c9 |
| Source note | uspto-grants-1997_12 |