o-Benzylbenzoic acid → 2-Benzylbenzoyl chloride

HRID 1940790Notes

Reaction equation

HRID 1940790 reaction equation
[C:1]1([CH2:7][C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10](O)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:19])=O>>[C:1]1([CH2:7][C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10]([Cl:19])=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 11924o-Benzylbenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 126823622-Benzylbenzoyl chloride

Procedure

A mixture of 5.0 g of 2-(phenylmethyl)benzoic acid in 5.0 ml of thionyl chloride is heated on a steam bath for 1 hour. The volatiles are evaporated in vacuo to give 5.74 g of the desired product as an oil. M+= 227 as methyl ester.

Workup

  1. temperatureis heated on a steam bath for 1 hour
  2. customThe volatiles are evaporated in vacuo

Sources & evidence

ORD record
ord-2c346ed242f4406689bbdc8140bb9678
Source dataset
uspto-grants-1997_12
Patent number
US05700796

Reaction notes

Loading…