Thionyl Chloride → 4-[[2-(Phenylmethyl)benzoyl]amino]benzoyl Chloride

HRID 1940793Notes

Reaction equation

HRID 1940793 reaction equation
[C:1]1([CH2:7][C:8]2[CH:25]=[CH:24][CH:23]=[CH:22][C:9]=2[C:10]([NH:12][C:13]2[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=2)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:28])=O>>[C:1]1([CH2:7][C:8]2[CH:25]=[CH:24][CH:23]=[CH:22][C:9]=2[C:10]([NH:12][C:13]2[CH:21]=[CH:20][C:16]([C:17]([Cl:28])=[O:18])=[CH:15][CH:14]=2)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 220996974-[[2-(Phenylmethyl)benzoyl]amino]benzoic Acid

Product 1

HCID 220996634-[[2-(Phenylmethyl)benzoyl]amino]benzoyl Chloride

Procedure

A mixture of 2.0 g of 4-[[2-(phenylmethyl)- benzoyl]amino]benzoic acid in 2.0 ml of thionyl chloride is heated on a steam bath for 1 hour. The volatiles are evaporated in vacuo to give 1.53 g of the desired product as an oil. M+ =346 as methyl ester.

Workup

  1. temperatureis heated on a steam bath for 1 hour
  2. customThe volatiles are evaporated in vacuo

Sources & evidence

ORD record
ord-d3c8562f064842a8b99d4c7ff6d1f86d
Source dataset
uspto-grants-1997_12
Patent number
US05700796

Reaction notes

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