Benzylamine → HCID 54552295, compound

HRID 1940960Notes

Reaction equation

HRID 1940960 reaction equation
[CH3:1][N:2]1[C:11]([CH2:12][C:13](O)=[O:14])=[C:10]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:9]2[C:4](=[CH:5][C:6]([CH3:23])=[C:7]([CH3:22])[CH:8]=2)[C:3]1=[O:24].[CH2:25]([NH2:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[CH2:25]([NH:32][C:13](=[O:14])[CH2:12][C:11]1[N:2]([CH3:1])[C:3](=[O:24])[C:4]2[C:9]([C:10]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[CH:8][C:7]([CH3:22])=[C:6]([CH3:23])[CH:5]=2)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 21463115HCID 21463115, compound

Product 1

HCID 54552295HCID 54552295, compound

Procedure

1,2-Dihydro-2,6,7-trimethyl-1-oxo-4-phenyl-3-isoquinolineacetic acid (Reference Example 56) and benzylamine were reacted (amidation) and treated in substantially the same manner as in Example 101 to yield the title compound as colorless crystals.

Workup

  1. additiontreated in substantially the same manner as in Example 101

Sources & evidence

ORD record
ord-c4b9664555704f27890c9ff2368d8f3b
Source dataset
uspto-grants-1997_12
Patent number
US05700810

Reaction notes

Loading…