HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 86751764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | HCID 85797117 | HCID 85797117 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 86751764 | HCID 86751764 | — |
Reaction Steps
1.74 g (22.7 mmol) of methyl chloroformate are added dropwise to a solution of 5 g (18.92 mmol) of ethyl (3-(4-(aminoiminomethyl)phenyl)ureido)acetate in 53 ml of triethylamine and 100 ml of DMF. After 7 d at room temperature, solid is filtered off and the filtrate is concentrated in vacuo. The residue is chromatographed on silica gel (ethyl acetate/methanol 95:5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703050 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-2e89fbbde2d54898bd608c82660b821c |
| Source note | uspto-grants-1997_12 |