Ammonia → HCID 86751770, compound

HRID 1941102Notes

Reaction equation

HRID 1941102 reaction equation
C(O[N:4]=[CH:5][C:6]1[CH:30]=[CH:29][C:9]([CH2:10][N:11]([O:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:12](=[O:20])[NH:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:8][CH:7]=1)C.[NH3:31]>C(O)C>[NH2:31][N:4]=[CH:5][C:6]1[CH:30]=[CH:29][C:9]([CH2:10][N:11]([O:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:12](=[O:20])[NH:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 54208840HCID 54208840, compound

Product 1

HCID 86751770HCID 86751770, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.83 g (6.84 mmol) of ethyl (3-(4-(ethoxyiminomethyl)benzyl)-3-benzyloxyureido)acetate are dissolved in 100 ml of ethanol and treated with 6.74 ml (6.84 mmol) of ethanolic ammonia solution. After 24 h at room temperature, the solvent is removed in vacuo and the residue is recrystallized from ethyl acetate/ether.

Workup

  1. customthe solvent is removed in vacuo
  2. customthe residue is recrystallized from ethyl acetate/ether

Sources & evidence

ORD record
ord-2a19c4a5b5384bcbb33ece7cceeb0826
Source dataset
uspto-grants-1997_12
Patent number
US05703050

Reaction notes

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