HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Fluorobenzoylmethyl)pyrrolidine → 1-Methyl-3-{2-[3-(4-fluorobenzoylmethyl)pyrrolidin-1-yl]ethyl}-5-methoxyindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Fluorobenzoylmethyl)pyrrolidine | HCID 11085030 | — |
| Reactant | 3-(2-Bromoethyl)-5-methoxy-1-methyl-1H-indole | HCID 21459918 | — |
| Solvent | Ethyl ketone | HCID 7288 | — |
| Product | 1-Methyl-3-{2-[3-(4-fluorobenzoylmethyl)pyrrolidin-1-yl]ethyl}-5-methoxyindole | HCID 9910588 | — |
Reaction Steps
Alkylation of 3-(4-fluorobenzoylmethyl)pyrrolidine by the brominated compound obtained in Stage 3 is carded out in diethyl ketone by following the procedure described in Stage 3 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703070 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-3e629deee7d94eb6bb359eaf92e7ec87 |
| Source note | uspto-grants-1997_12 |