HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → HCID 54439326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 53652232 | HCID 53652232 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54439326 | HCID 54439326 | — |
Reaction Steps
(3β,5α,11β,12β,25R)-3-(t-butyldimethylsilyloxy)-11-(trimethylsilyloxy)-12-acetoxyspirostane was deacetylated by treatment with lithium aluminum hydride in THF followed by catious addition aqueous ammonium chloride. The resulting title compound suffered 11 to 12 silyl group migration on silica gel, and thus had to used unpurified.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703052 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-24dd1b6964cc4421aed684d6fef886c1 |
| Source note | uspto-grants-1997_12 |