HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrofluoric Acid → HCID 22872545, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrofluoric Acid | HCID 14917 | — |
| Reactant | 86023-87-2 | HCID 158910 | — |
| Reactant | HCID 54210416 | HCID 54210416 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 22872545 | HCID 22872545 | — |
Reaction Steps
The title compound was synthesized from (3β,5α,11β,25R)-3-(t-butyldimethylsilyoxy)-11-(trimethylsilyoxy)spirostan-12-one was desilylated with hydrofluoric acid in acetonitrile according to the procedure described in J. Am. Chem. Soc., 1972, 94, 6190. The title compound must be carefully handled because it will rearrange to (3β,5α,12β,25R)-spirostan-3,12-diol-11-one if exposed to base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703052 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-2ca07e3ede394ab4b599e075215396df |
| Source note | uspto-grants-1997_12 |