反应详情

A mixture of 0.5 g (0.8 mmol) of N,N'-Bis[2-(1,2-dihydro-1,3-dioxo-3H-dibenz[de,h]isoquinolin-2-yl)ethyl]-1,3-propanediamine and 1 ml of 36% formaldehyde in 100 ml of ethanol was refluxed for 7 hours. The solid was filtered, washed, dried, and recrystallized from toluene. 0.3 g (58%) of N,N'-bis[2-(1,2-dihydro-1,3-dioxo-3H-dibenz[de,h]isoquinolin-2-yl)ethyl]hexahydropyrimidine were obtained. M.p. 222° C. (toluene).

1. temperaturewas refluxed for 7 hours
2. filtrationThe solid was filtered
3. washwashed
4. customdried
5. customrecrystallized from toluene