HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Benzonitrile, 4-[3-(4-fluorophenyl)-1-oxo-2-propenyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | 4'-Cyanoacetophenone | HCID 74044 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Benzonitrile, 4-[3-(4-fluorophenyl)-1-oxo-2-propenyl]- | HCID 4811028 | — |
Reaction Steps
4-Acetylbenzonitrile (14.5 g, 0.1 mol) and 4-fluorobenzaldehyde (12.1 g, 0.1 mol) are dissolved in methanol (150 ml) and solid sodium hydroxide is added to make the solution alkaline. The mixture is stirred in room temperature for 6 hours. The product is filtered off and washed with methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703109 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-45428deecaa847ddb8fbde3a87481b2a |
| Source note | uspto-grants-1997_12 |