HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Imidazol-1-ylmethyl)benzonitrile → 1-[1-(4-cyanophenyl)-3-(4-fluorophenyl)-2-hydroxypropyl]-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Imidazol-1-ylmethyl)benzonitrile | HCID 1236449 | — |
| Reactant | 2-(4-Fluorophenyl)acetaldehyde | HCID 11126322 | — |
| Product | 1-[1-(4-cyanophenyl)-3-(4-fluorophenyl)-2-hydroxypropyl]-1H-imidazole | HCID 21843581 | — |
Reaction Steps
1-[1-(4-cyanophenyl)-3-(4-fluorophenyl)-2-hydroxypropyl]-1H-imidazole is prepared according to the procedure of Example 1 using 1-(4-cyanobenzyl)-imidazole and 4-fluorophenylacetaldehyde as starting materials. The product is purified by flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703109 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-33f6d369c83b48d4b4fd9a13f3b3a73f |
| Source note | uspto-grants-1997_12 |