HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 57281946, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 21460714 | HCID 21460714 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57281946 | HCID 57281946 | 95% |
Reaction Steps
Dissolve 3-[(2-benzylphenacyl)methylamino]-2-carbethoxy-4,6-dichloro-1-tert-butyloxycarbonyl-indole (320 mg, 0.55 mmol) in methylene chloride (5 mL). Add trifluoroacetic acid (1 mL) and stir at room temperature for 3 hours. Evaporate the solvent in vacuo and recrystallize (ethyl acetate/hexane) to give the title compound (250 mg, 95%); mp 208°-209° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703107 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-0abf3210ba01458db97de06d90861e51 |
| Source note | uspto-grants-1997_12 |