HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 57123645, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 21460699 | HCID 21460699 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57123645 | HCID 57123645 | 74% |
Reaction Steps
Dissolve 3-[(p-fluorophenacyl)methylamino]-2-carbethoxy-4,6-dichloro-1-(tert-butyloxycarbonyl)-indole (1.2 g, 2.35 mmol) in methylene chloride. Add trifluoracetic acid and stir for 2 hours. Concentrate the reaction in vacuo and recrystallize the residue from hot ethyl acetate/hexane to yield the title compound (720 mg, 74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703107 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-800bf061654e42ab9c69a9eaf075e755 |
| Source note | uspto-grants-1997_12 |