Methanol → 2-[4-[3-(Aminomethyl)pyrrolidin-1-yl]-6-fluoroquinazolin-2-yl]phenol
Reaction equation
[CH2:1]([c:5]1[cH:6][cH:7][cH:9][cH:10][cH:11]1)[N:8]([C:2](=[O:3])[O-:4])[CH2:12][CH:13]1[CH2:14][N:15]([c:18]2[n:19][c:20](-[c:29]3[c:30]([OH:35])[cH:31][cH:32][cH:33][cH:34]3)[n:21][c:22]3[cH:23][cH:24][c:25]([F:28])[cH:26][c:27]23)[CH2:16][CH2:17]1.[CH3:36][OH:37]>>[NH2:8][CH2:12][CH:13]1[CH2:14][N:15]([c:18]2[n:19][c:20](-[c:29]3[c:30]([OH:35])[cH:31][cH:32][cH:33][cH:34]3)[n:21][c:22]3[cH:23][cH:24][c:25]([F:28])[cH:26][c:27]23)[CH2:16][CH2:17]1Participants
3
Sources & evidence
- ORD record
- ord-f08b4d71f39c48b9998767fb16e7e09b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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