Methanesulfonyl chloride → (+/-)5-[(3,5-Bis-trifluoromethyl-benzyl)-methanesulfonyl-amino]-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylic acid isopropyl ester
Reaction equation
[CH3:37][S:38]([Cl:39])(=[O:40])=[O:41].[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[c:8]2[c:9]([cH:33][cH:34][cH:35][cH:36]2)[CH:10]([N:14]([CH2:15][c:16]2[cH:17][c:18]([C:26]([F:27])([F:28])[F:29])[cH:19][c:20]([C:22]([F:23])([F:24])[F:25])[cH:21]2)[C:30](=[O:31])[CH3:32])[CH2:11][CH2:12][CH2:13]1>>[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[c:8]2[c:9]([cH:33][cH:34][cH:35][cH:36]2)[CH:10]([N:14]([CH2:15][c:16]2[cH:17][c:18]([C:26]([F:27])([F:28])[F:29])[cH:19][c:20]([C:22]([F:23])([F:24])[F:25])[cH:21]2)[S:38]([CH3:37])(=[O:40])=[O:41])[CH2:11][CH2:12][CH2:13]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-4dbc80744b784e4c9d7bc9a579b3bf23
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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