HCID 86751788, compound → HCID 70271251, compound

Participants

Reaction Steps

To a solution of 43 (1.06 g, 2.27 mol) in 35 mL of methanol was added 10% Pd/C catalyst (127 mg) and the mixture was hydrogenated on a Parr shaker apparatus at 45 PSI for 2 hrs. The solution was filtered, evaporated, and the residue was dried by pumping at <1 mm Hg vacuum for 10 hrs to afford 0.836 g (98% yield) of product 44 as a colorless foam. TLC (silica; CH2Cl2, methanol, acetic acid: 27, 3, 1) Rf=0.40.

Provenance & Evidence