Propanal → HCID 86751791, compound

HRID 1941524Notes

Reaction equation

HRID 1941524 reaction equation
[Br:1][CH2:2][CH:3]1[O:12][CH2:11][CH:10]2[CH:6]([O:7][C:8](C)([CH3:13])[O:9]2)[CH2:5][O:4]1.BrCC1OCC(O)C(O)CO1.C(=O)CC>>[Br:1][CH2:2][CH:3]1[O:12][CH2:11][CH:10]2[CH:6]([O:7][CH:8]([CH3:13])[O:9]2)[CH2:5][O:4]1

Participants

4

Reactant 3

HCID 527PropanalHCID 21461382HCID 21461382, compoundHCID 21461387HCID 21461387, compound

Product 1

HCID 86751791HCID 86751791, compoundYield 71%

Procedure

4-Bromomethyl-9-methyl-3,5,8,10-tetraoxabicyclo [5.3.0]decane was prepared in a similar way to 4-bromomethyl-9,9-dimethyl-3,5,8, 10-tetraoxabicyclo[5.3.0]decane starting from 132 mmol (30 g) of 2-bromomethyl-5,6-dihydroxy-1,3-dioxepane and from 0.816 mol (60 ml) of propionaldehyde, fractional distillation giving 25 g (71% yield) from 100° to 102° C. (0.4 mbar).

Workup

  1. customgiving 25 g (71% yield) from 100° to 102° C. (0.4 mbar)

Sources & evidence

ORD record
ord-8bb0d22f9f0943599a319f0f396d0448
Source dataset
uspto-grants-1997_12
Patent number
US05703249

Reaction notes

Loading…