HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → (2-Amino-5-hydroxyphenyl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | HCID 14025389 | HCID 14025389 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2-Amino-5-hydroxyphenyl)acetonitrile | HCID 19607200 | — |
Reaction Steps
A suspension of 5.4 g of 2-nitro 5-benzyloxyphenylacetonitrile, 5.4 ml of cyclohexene, 22 ml of ethanol and 3 g of 10% palladium on activated charcoal was refluxed for five hours. The suspension was then hot filtered and the filtrate evaporated. The residue was recrystallised from ethanol to produce dark beige crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703266 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-9f85d6aa879d4d139c24221fd3f34af8 |
| Source note | uspto-grants-1997_12 |