HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Hydroxyacetophenone → 5-(4-{2-[1-(4-Hydroxyphenyl)ethylideneaminooxy]ethoxy}benzyl)thiazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Hydroxyacetophenone | HCID 7469 | — |
| Reactant | 5-(4-[2-Aminooxyethoxy)benzyl]thiazolidine-2,4-dione hydrochloride | HCID 21833965 | — |
| Product | 5-(4-{2-[1-(4-Hydroxyphenyl)ethylideneaminooxy]ethoxy}benzyl)thiazolidine-2,4-dione | HCID 136395967 | 84.2% |
Reaction Steps
Following a procedure similar to that described in Example 40(f), but using 0.33 g of 4'-hydroxyacetophenone and 0.70 g of 5-[4-(2-aminooxyethoxy)benzyl]-thiazolidine-2,4-dione hydrochloride [prepared as described in Example 40(e)], 0.74 g of the title compound, melting at 157°-159° C., was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703096 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-90c8788440504ba1936d0bba5224b184 |
| Source note | uspto-grants-1997_12 |