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HRID1941810

反应详情

EQUATION

反应方程式

HRID 1941810 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(OC(F)F)cn1
HCID57475871

未命名化合物

结构：CC1(C)OC(N)=N[C@](C)(c2cc(N)ccc2F)C1(F)F
HCID58304251

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)OC(N)=N[C@](C)(c2cc(NC(=O)c3ccc(OC(F)F)cn3)ccc2F)C1(F)F
HCID53240502

未命名化合物

PROCEDURE

实验过程

The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4,6,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-2) and 5-difluoromethoxy-pyridine-2-carboxylic acid (CAS1174323-34-2, WO2009091016) following procedure I yielded the title compound as a white foam. MS (ISP): m/z=459.2 [M+H]+.