HRID1941811

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID57475872

未命名化合物

反应SMILES：CC1(C)OC(N)=N[C@](C)(c2cc(N)ccc2F)C1(F)F

HCID58304251

未命名化合物

PRODUCTS

产物

反应SMILES：CC1(C)OC(N)=N[C@](C)(c2cc(NC(=O)c3ccc(OCC(F)F)cn3)ccc2F)C1(F)F

HCID53240503

未命名化合物

PROCEDURE

实验过程

The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4,6,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-2) and 5-(2,2-difluoro-ethoxy)-pyridine-2-carboxylic acid (CAS1097730-45-4, WO2009091016) following procedure I yielded the title compound as a white solid. MS (ISP): m/z=473.1 [M+H]+.