HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57475876, compound → HCID 67234182, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57475876 | HCID 57475876 | — |
| Reactant | (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine | HCID 58304207 | — |
| Product | HCID 67234182 | HCID 67234182 | — |
Reaction Steps
The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-1) and 5-cyclopropylethynyl-pyridine-2-carboxylic acid (CAS1174322-62-3, WO2009091016) following procedure I yielded the title compound as a white solid. MS (ISP): m/z=429.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389513B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-13fc45b93a324d9db5e716b39f12b16a |
| Source note | uspto-grants-2013_03 |